Work Streams

The NMPN has been divided into 10 work streams, each with different responsibilities to deliver their own outcomes and deliverables in line with the NMPN Project Manager.


Intelligent search informatics
Lead Prof Jon Garibaldi

Creating Informatics Spider (IfS)with search capabilities into UKCRC Tissue Directories and, ultimately, NHS clinical data.


Computational data analytics

Lead Prof John Garibaldi

Advanced data analysis algorithms for representing data and empirical modelling data (to identify biomarkers) and mechanistic modelling.


Histogenic Molecular Mapping (HMM)

Lead Prof Mohammad Ilyas

Novel algorithms providing for the needs of biomarker research projects and for the needs of diagnostic service delivery of Empath.


Chronic fibrotic lung disease

Lead Dr Gisli Jenkins

Molecular endotyping of chronic fibrotic lung disease.


Activity of destructive lung diseases

Lead Prof Simon Johnson

Markers of tissue remodelling to determine the activity of destructive lung diseases.


Cystic Fibrosis (CF)

Lead Dr Andrew Fogarty

Molecular microbiological signal to stratify patients and monitor therapeutic responses in Cystic Fibrosis (CF)


Non-alcoholic Fatty Liver Disease (NAFLD)

Lead Prof Guruprasad Aithal

Stratification of chronic hepatitis B (HBV) and evaluation of efficacy of interventions.


Chronic Hepatitis B (HBV)

Lead Prof Will Irving

Stratification of chronic hepatitis B (HBV) and evaluation of efficacy of interventions.


H. Pylori infection

Dr Karen Robinson

Prognostic biomarkers for Helicobacter pylori-induced gastro-duodenal disease.


Training courses

Leads Dr Abhik Mukherjee & Prof Mohammad Ilyas

Molecular pathology training courses



Rebecca Braybrooke

The research, infrastructure & training work streams WS1-8 will fit into the management and governance structure. This management/governance structure will create a dynamic environment where work streams are monitored, shaped and contracted or expanded depending on their success