Work Streams

The NMPN has been divided into 10 work streams, each with different responsibilities to deliver their own outcomes and deliverables in line with the NMPN Project Manager.

1

Intelligent search informatics
Lead Prof Jon Garibaldi

Creating Informatics Spider (IfS)with search capabilities into UKCRC Tissue Directories and, ultimately, NHS clinical data.

2

Computational data analytics

Lead Prof John Garibaldi

Advanced data analysis algorithms for representing data and empirical modelling data (to identify biomarkers) and mechanistic modelling.

3

Histogenic Molecular Mapping (HMM)

Lead Prof Mohammad Ilyas

Novel algorithms providing for the needs of biomarker research projects and for the needs of diagnostic service delivery of Empath.

4

Chronic fibrotic lung disease

Lead Dr Gisli Jenkins

Molecular endotyping of chronic fibrotic lung disease.

5

Activity of destructive lung diseases

Lead Prof Simon Johnson

Markers of tissue remodelling to determine the activity of destructive lung diseases.

6

Cystic Fibrosis (CF)

Lead Dr Andrew Fogarty

Molecular microbiological signal to stratify patients and monitor therapeutic responses in Cystic Fibrosis (CF)

7a

Non-alcoholic Fatty Liver Disease (NAFLD)

Lead Prof Guruprasad Aithal

Stratification of chronic hepatitis B (HBV) and evaluation of efficacy of interventions.

7b

Chronic Hepatitis B (HBV)

Lead Prof Will Irving

Stratification of chronic hepatitis B (HBV) and evaluation of efficacy of interventions.

8

H. Pylori infection

Dr Karen Robinson

Prognostic biomarkers for Helicobacter pylori-induced gastro-duodenal disease.

9

Training courses

Leads Dr Abhik Mukherjee & Prof Mohammad Ilyas

Molecular pathology training courses

10

Management/Governance

Rebecca Braybrooke

The research, infrastructure & training work streams WS1-8 will fit into the management and governance structure. This management/governance structure will create a dynamic environment where work streams are monitored, shaped and contracted or expanded depending on their success