Work Streams
The NMPN has been divided into 10 work streams, each with different responsibilities to deliver their own outcomes and deliverables in line with the NMPN Project Manager.
1
Intelligent search informatics
Lead Prof Jon Garibaldi
Creating Informatics Spider (IfS)with search capabilities into UKCRC Tissue Directories and, ultimately, NHS clinical data.
2
Computational data analytics
Advanced data analysis algorithms for representing data and empirical modelling data (to identify biomarkers) and mechanistic modelling.
3
Histogenic Molecular Mapping (HMM)
Novel algorithms providing for the needs of biomarker research projects and for the needs of diagnostic service delivery of Empath.
4
Chronic fibrotic lung disease
Molecular endotyping of chronic fibrotic lung disease.
5
Activity of destructive lung diseases
Markers of tissue remodelling to determine the activity of destructive lung diseases.
6
Cystic Fibrosis (CF)
Molecular microbiological signal to stratify patients and monitor therapeutic responses in Cystic Fibrosis (CF)
7a
Non-alcoholic Fatty Liver Disease (NAFLD)
Stratification of chronic hepatitis B (HBV) and evaluation of efficacy of interventions.
7b
Chronic Hepatitis B (HBV)
Stratification of chronic hepatitis B (HBV) and evaluation of efficacy of interventions.
8
H. Pylori infection
Prognostic biomarkers for Helicobacter pylori-induced gastro-duodenal disease.
9
Training courses
Leads Dr Abhik Mukherjee & Prof Mohammad Ilyas
Molecular pathology training courses
10
Management/Governance
The research, infrastructure & training work streams WS1-8 will fit into the management and governance structure. This management/governance structure will create a dynamic environment where work streams are monitored, shaped and contracted or expanded depending on their success