Christine Blancher & Ian Tomlinson:
The Highs And Lows Of Microarrays / Data Interpretation Of Microarrays
Ian Tomlinson is Professor of Molecular and Population Genetics at the University of Oxford and Head of the Oxford Centre for Cancer Gene Research. His interests include identification of high- and low-penetrance tumour predisposition genes and functional cancer genetics. He has a longstanding interest in cancer evolution, including simple mathematical and descriptive models, and experimental analysis of tumour genomes.
Christine Blancher completed a PhD in Molecular and Cellular Biology at Paris V University (CNRS - Development and Immunity of Central Nervous System) on isolation and characterization of a novel cDNA expressed during the neuroretina development. She was trained in cancer biology for 4 years as a post-doctoral fellow in the Cancer Research UK unit of Prof. A.L. Harris at the Weatherall Institute of Molecular Medicine in Oxford (UK). Her project focused on the role of the hypoxic response pathway in tumour biology.
She returned to Paris for a year as a post-doctoral fellow in the INSERM Unit of Prof. Y. Courtois where she worked on cell cycle arrest during neuroretina development and then went to work in Australia as a Senior Research Officer in the Breast and Ovarian Cancer Genetics unit of Pr I. G. Campbell at the Peter McCallum Cancer Institute in Melbourne. She came back to Oxford to work in the Diabetes Genetics Group of Dr D. Gauguier at the Wellcome Trust Centre for Human Genetics where she gained experience in gene expression and microarray technologies.
She joined the Core Genomics group in 2006 as a senior R&D Scientist optimising chIP on Affymetrix array and characterizing mRNA targets for hypoxia regulated miRNAs in Human Breast Cancer cells. Since 2010, Christine is managing the High Throughput Genomics array service, using her expertise in Genotyping, Cytogenetics, Epigenetics and Gene Expression to establish and maintain business relationships with worldwide scientists using the service and guiding users through experimental design and use of the appropriate technology.